Δημοσιεύσεις

Οι δημοσιεύσεις σχετικές με το μελάνωμα από τα μέλη της Μονάδας και συνεργαζόμενων μονάδων, τμημάτων και κλινικών περιλαμβάνουν τις ακόλουθες:

• Michelakis D, Lasithiotakis K, Messaritakis I, Ioannou C, Perisynakis K, Souglakos I, Stamatiou D, Chlouverakis G, de Bree E, Romanos I, Zoras O. A feasibility study of circulating melanoma cells in the perioperative context of hyperthermic isolated limb perfusion (HILP) in 20 patients. Int J Hyperthermia 2021;38:70-78. doi: 10.1080/02656736.2021.1874062. PMID: 33487077

• Maurichi A, Miceli R, Patuzzo R, Barretta F, Gallino G, Mattavelli I, Barbieri C, Leva A, Cortinovis U, Tolomio E, Sant M, Castelli G, Zichichi L, Pellacani G, Stanganelli I, Simonacci M, Manganoni A, Del Forno C, Caresana G, Harwood C, Bergamaschi D, Lasithiotakis K, Bennett D, Espeli V, Mangas C, Leoni Parvex S, Valeri B, Cossa M, Barisella M, Pellegrinelli A, Miranda C, Anichini A, Mortarini R, Zoras O, Santinami M. Analysis of sentinel node biopsy and clinicopathologic features as prognostic factors in patients with atypical melanocytic tumors. J Natl Compr Canc Netw 2020;18:1327-1336. doi: 10.6004/jnccn.2020.7582. PMID: 33022642

• Maurichi A, Miceli R, Eriksson H, Newton-Bishop J, Nsengimana J, Chan M, Hayes AJ, Heelan K, Adams D, Patuzzo R, Barretta F, Gallino G, Harwood C, Bergamaschi D, Bennett D, Lasithiotakis K, Ghiorzo P, Dalmasso B, Manganoni A, Consoli F, Mattavelli I, Barbieri C, Leva A, Cortinovis U, Espeli V, Mangas C, Quaglino P, Ribero S, Broganelli P, Pellacani G, Longo C, Del Forno C, Borgognoni L, Sestini S, Pimpinelli N, Fortunato S, Chiarugi A, Nardini P, Morittu E, Florita A, Cossa M, Valeri B, Milione M, Pruneri G, Zoras O, Anichini A, Mortarini R, Santinami M. Factors affecting sentinel node metastasis in thin (T1) cutaneous melanomas: development and external validation of a predictive nomogram. J Clin Oncol 2020;38:1591-1601. doi: 10.1200/JCO.19.01902. PMID: 32167862

• de Bree E, Michelakis D, Ioannou C, Stamatiou D, Romanos J, Zoras O.   Isolated limb perfusion for in-transit melanoma metastases.Hell Surg Oncol 2017;8:17-28.

• Krasagakis K, Tsentelierou E, Chlouverakis G, Stathopoulos EN. Topography of protein kinase C βii in benign and malignant melanocytic lesions. Int J Surg Pathol 2017;25:497-501. doi: 10.1177/1066896917706026. PMID: 28436290

• Stamatiou D, Ioannou CV, Kontopodis N, Michelakis D, Perisinakis K, Lasithiotakis K, Zoras O. Hyperthermic isolated limb perfusion. The switch from Steinmann pins to Omni-tract assisted isolation. J Surg Res 2017;213:147-157. doi: 10.1016/j.jss.2017.02.023. PMID: 28601307

• Lasithiotakis K, Zoras O. Metastasectomy in cutaneous melanoma. Eur J Surg Oncol 2017;43:572-580. doi: 10.1016/j.ejso.2016.11.001. PMID: 27889195

• de Bree E, Tzardi M, Michelakis D, Kalbakis K, Zoras O. Small bowel metastasis of cuteneous melanoma as a cause of anaemia. Hell Surg Oncol 2015;6:89-94.

• de Bree E, Gkionis I, Kassotakis D, de Bree RA comparison between surgical management of cutaneous melanomalocalized in the head and neck region and those at other sites. Hell Surg Oncol 2015;6:53-60.

• Bluemel C, Herrmann K, Giammarile F, Nieweg OE, Dubreuil J, Testori A, Audisio RA, Zoras O, Lassmann M, Chakera AH, Uren R, Chondrogiannis S, Colletti PM, Rubello D. EANM practice guidelines for lymphoscintigraphy and sentinel lymph node biopsy in melanoma. Eur J Nucl Med Mol Imaging 2015;42:1750-1766. doi: 10.1007/s00259-015-3135-1. PMID: 26205952

• Zoras O, Lasithiotakis K, Balch CM. Uncertainties in the management of melanoma nodal metastasis. Eur J Surg Oncol 2015;41:811-813. doi: 10.1016/j.ejso.2015.04.011. PMID: 25980747

• de Bree E, de Bree R. Implications of the MSLT-1 for sentinel lymph node biopsy in cutaneous head and neck melanoma. Oral Oncol 2015;51:629-633. doi: 10.1016/j.oraloncology.2015.04.013. PMID: 25936652

• de Bree E, de Bree R. Verbetering van afstandsvrije en melanoomspecifiek overleving door toepassing van de schildwachtklierprocedure bij patienten met een middeldik melanoom en occulte lymfekliermetastasen. Ned Tijdschr Oncol 2014;11:176-178.

• de Bree E. Survival improvement in patients with intermediate thickness melanoma and occult lymph node metastases by sentinel lymph node biopsy. Hell Surg Oncol 2014;5:6-9.

• Göppner D, Müller J, Krüger S, Franke I, Gollnick H, Quist SR. High incidence of naevi-associated BRAF wild-type melanoma and dysplastic naevi under treatment with the class I BRAF inhibitor vemurafenib. Acta Derm Venereol 2014;94:517-520. doi: 10.2340/00015555-1813. PMID: 24531394

• Maurichi A, Miceli R, Camerini T, Mariani L, Patuzzo R, Ruggeri R, Gallino G, Tolomio E, Tragni G, Valeri B, Anichini A, Mortarini R, Moglia D, Pellacani G, Bassoli S, Longo C, Quaglino P, Pimpinelli N, Borgognoni L, Bergamaschi D, Harwood C, Zoras O, Santinami M. Prediction of survival in patients with thin melanoma: results from a multi-institution study. J Clin Oncol 2014;32:2479-2485.

• Tosca A, Kokolakis A, Lasithiotakis K, Zacharopoulos A, Zabulis X, Marnelakis I, Ripoll J, Stephanidis C. Development of a three-dimensional surface imaging system for melanocytic skin lesion evaluation. J Biomed Opt 2013;18:16009.

• Kokolakis A, Zacharakis G, Krasagakis K, Lasithiotakis K, Favicchio R, Spiliopoulos G, Giannikaki E, Ripoll J, Tosca A. Prehistological evaluation of benign and malignant pigmented skin lesions with optical computed tomography. J Biomed Opt 2012;17:066004. doi: 10.1117/1.JBO.17.6.066004. PMID: 22734760

• de Bree E. Sentinel lymph node biopsy and survival in the elderly patients with cutaneous melanoma. Br J Surg 2011;98:1407. doi: 10.1002/bjs.7591. PMID: 21887776

• Lasithiotakis KG, Kokolakis A, Giannikaki E, Krasagakis K, Tosca A. Factors associated with the prevalence of atypical nevus in a Mediterranean pigmented skin lesion clinic. Melanoma Res 2011;21:469-473. doi: 10.1097/CMR.0b013e32834941f9. PMID: 21760555

• Lasithiotakis K, Economou G, Gogas H, Ioannou C, Perisynakis K, Filis D, Kastana O, Bafaloukos D, Decatris M, Catodritis N, Frangia K, Papadakis G, Magarakis M, Tsoutsos D, Chrysos E, Chalkiadakis G, Zoras O. Hyperthermic isolated limb perfusion for recurrent melanomas and soft tissue sarcomas: feasibility and reproducibility in a multi-institutional Hellenic collaborative study. Oncol Rep 2010;23:1077-1083. doi: 10.3892/or_00000735. PMID: 20204294

• Parara S, de Bree E, Takos D, Giannikaki E, Melissas J, Tsiftsis DD. Melanoma of the vulva: a pigmented lesion is also significant in a non-sun-expose area. Arch Gynecol Obstet 2009;280:831-834. doi: 10.1007/s00404-009-1011-6. PMID: 19255768

• Santinami M, Carbone A, Crippa F, Maurichi A, Pellitteri C, Ruggeri R, Zoras O, Patuzzo R. Radical dissection after positive groin sentinel biopsy in melanoma patients: rate of further positive nodes.  Melanoma Res 2009;19:112-118. doi: 10.1097/CMR.0b013e328329fe7d. PMID: 19282788

• Chalkiadaki G, Nikitovic D, Berdiaki A, Sifaki M, Krasagakis K, Katonis P, Karamanos NK, Tzanakakis GN. Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism. Int J Biochem Cell Biol 2009;41:1323-1331. doi: 10.1016/j.biocel.2008.11.008. PMID: 19110070

• Stavroulaki M, Kardassis D, Chatzaki E, Sakellaris G, Lindschau C, Haller H, Tosca A, Krasagakis K. Exposure of normal human melanocytes to a tumor promoting phorbol ester reverses growth suppression by transforming growth factor beta. J Cell Physiol 2008;214:363-370. doi: 10.1002/jcp.21207. PMID: 17654516

• Nikitovic D, Assouti M, Katonis P, Krasagakis K, Karamanos NK, Tzanakakis GN. Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines. Int J Biochem Cell Biol 2008;40:72-83. doi: 10.1016/j.biocel.2007.06.019. PMID: 17706452

• de Bree E, Μανιός Α, Τσιφτσής ΔΔ. Η αντιμετώπιση των επιχώριων λεμφαδένων στο μελάνωμα του δέρματος. Ελληνική Χειρουργική 2007;79:284-295.

• de Bree E, de Bree R, Μανιός Α, Τσιφτσής ΔΔ. Το κακόηθες μελάνωμα του βλεννογόνου της ρινός και των παραρρίνιων κόλπων. Ελληνική Οτορινολαρυγγολογία – Χειρουργική Κεφαλής & Τραχήλου 2007;28:136-140.

• de Bree E, Μανιός Α, de Bree R, Τσιφτσής ΔΔ. Το κακόηθες μελάνωμα του δέρματος της ρινός. Ελληνική Χειρουργική Ογκολογία 2006;6:70-80.

• Lasithiotakis K, Leiter U, Krüger-Krasagakis S, Tosca A, Garbe C. Comparative analysis of incidence and clinical features of cutaneous malignant melanoma in Crete (Greece) and southern Germany (central Baden-Wurttemberg). Br J Dermatol 2006;154:1123-1127. doi: 10.1111/j.1365-2133.2006.07163.x. PMID: 16704644

• Kalogeraki A, Garbagnati F, Darivianaki K, Delides GS, Santinami M, Stathopoulos EN, Zoras O. HSP-70, C-myc and HLA-DR expression in patients with cutaneous malignant melanoma metastatic in lymph nodes. Anticancer Res 2006;26:3551-3554. PMID: 17094481

• Manousaki AG, Manios AG, Tsompanaki EI, Panayiotides JG, Tsiftsis DD, Kostaki AK, Tosca AD. A simple digital image processing system to aid in melanoma diagnosis in an everyday melanocytic skin lesion unit: a preliminary report. Int J Dermatol 2006;45:402-410. doi: 10.1111/j.1365-4632.2006.02726.x. PMID: 16650167

• Lasithiotakis K, Krüger-Krasagakis S, Manousaki A, Ioannidou D, Panagiotides I, Tosca A. The incidence of cutaneous melanoma on Crete, Greece. Int J Dermatol 2006;45:397-401. doi: 10.1111/j.1365-4632.2006.02492.x. PMID: 16650166

• Manousaki AG, Manios AG, Tsompanaki EI, Tosca AD. Use of color texture in determining the nature of melanocytic skin lesions--a qualitative and quantitative approach. Comput Biol Med 2006;36:419-427. doi: 10.1016/j.compbiomed.2005.01.004. PMID: 16488774

• Sifaki M, Assouti M, Nikitovic D, Krasagakis K, Karamanos NK, Tzanakakis GN. Lumican, a small leucine-rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes. IUBMB Life 2006;58:606-610. doi: 10.1080/15216540600951605. PMID: 17050378

• Krasagakis K, Lindschau C, Fimmel S, Eberle J, Quass P, Haller H, Orfanos CE. Proliferation of human melanoma cells is under tight control of protein kinase C alpha. Proliferation of human melanoma cells is under tight control of protein kinase C alpha. J Cell Physiol 2004;199:381-387. doi: 10.1002/jcp.10434. PMID: 15095285

• de Bree E, Μανιός Α, Τσιφτσής ΔΔ. Η τοπική χειρουργική αντιμετώπιση του εντοπισμένου μελανώματος του δέρματος και τα όρια εκτομής’. Ελληνική Χειρουργική 2004;76:236-244.

• Koukouraki S. Preoperative radionuclide lymphangiography and sentinel node localization with radionuclide techniques. Advantages and ambiguous aspects. Hell J Nucl Med 2004;7:5-13. PMID: 16868635

• Lasithiotakis K, Krüger-Krasagakis S, Ioannidou D, Pediaditis I, Tosca A. Epidemiological differences for cutaneous melanoma in a relatively dark-skinned Caucasian population with chronic sun exposure. Eur J Cancer 2004;40:2502-2507. doi: 10.1016/j.ejca.2004.06.032. PMID: 15519526

• Hoffmann K, Gambichler T, Rick A, Kreutz M, Anschuetz M, Grünendick T, Orlikov A, Gehlen S, Perotti R, Andreassi L, Newton Bishop J, Césarini JP, Fischer T, Frosch PJ, Lindskov R, Mackie R, Nashan D, Sommer A, Neumann M, Ortonne JP, Bahadoran P, Penas PF, Zoras U, Altmeyer P. Diagnostic and neural analysis of skin cancer (DANAOS). A multicentre study for collection and computer-aided analysis of data from pigmented skin lesions using digital dermoscopy. Br J Dermatol 2003;149:801-809. doi: 10.1046/j.1365-2133.2003.05547.x. PMID: 14616373

• Krasagakis K, Fimmel S, Genten D, Eberle J, Quas P, Ziegler W, Haller H, Orfanos CE. Lack of protein kinase C (PKC)-beta and low PKC-alpha, -delta, -epsilon, and -zeta isozyme levels in proliferating human melanoma cells. Int J Oncol 2002;20:865-871. PMID: 11894137

• Kontochristopoulos GJ, Stavropoulos PG, Krasagakis K, Goerdt S, Zouboulis CC.Differentiation between merkel cell carcinoma and malignant melanoma: An immunohistochemical study.Differentiation between merkel cell carcinoma and malignant melanoma: An immunohistochemical study. Dermatology 2000;201:123-126. doi: 10.1159/000018454. PMID: 11053914

• Τσαγκατάκης Θ, Κουκουράκη Σ, Ασκοξυλάκης Ι, de Bree E, Στεφανάκη Κ, Τσιφτσής Δ. Η ραδιοϊσοτοπική και χρωματογραφική εντόπιση του λεμφαδένα φρουρού σε καρκίνο του μαστού και σε μελάνωμα του άκρου. Ελληνική Χειρουργική 2000;72:476-480.

• de Bree E, Χριστοδουλάκης Μ, Τσιφτσής Δ. Η αντιμετώπιση των νεοπλασμάτων των άκρων με διατήρηση του σκέλους. Μέρος 2: Μελάνωμα. Ελληνική Χειρουργική 1999;71:382-392.

• Krasagakis K, Krüger-Krasagakes S, Fimmel S, Eberle J, Tholke D, von der Ohe M, Mansmann U, Orfanos CE. Desensitization of melanoma cells to autocrine TGF-beta isoforms. J Cell Physiol 1999;178:179-187. doi: 10.1002/(SICI)1097-4652(199902)178:2<179::AID-JCP7>3.0.CO;2-5. PMID: 10048582

• Krasagakis K, Thölke D, Farthmann B, Eberle J, Mansmann U, Orfanos CE.Elevated plasma levels of transforming growth factor (TGF)-beta1 and TGF-beta2 in patients with disseminated malignant melanoma. Br J Cancer 1998;77:1492-1494. doi: 10.1038/bjc.1998.245. PMID: 9652767

• Farthmann B, Eberle J, Krasagakis K, Gstottner M, Wang N, Bisson S, Orfanos CE. RT-PCR for tyrosinase-mRNA-positive cells in peripheral blood: evaluation strategy and correlation with known prognostic markers in 123 melanoma patients. J Invest Dermatol 1998;110:263-267. doi: 10.1046/j.1523-1747.1998.00131.x. PMID: 9506446

• de Bree E, Sanidas E, Tzardi M, Gaki B, Tsiftsis D. Malignant melanoma of the penis.Eur J Surg Oncol 1997;23:277-279. doi: 10.1016/s0748-7983(97)92724-4. PMID: 9236908

• de Bree E, Ρωμανός Ι, Ζερβός Κ, Κοκκινάκης Φ, Τσιφτσής Δ. Διεγχειρητιή εντόπιση του ‘λεμφαδένα φρουρού’ σε μελάνωμα του άκρου με τη χορήγηση κυανού του μεθυλενίου ενδοδερμικώς. Ελληνική Χειρουργική 1997;69:187-190.

• de Bree E, Ρωμανός Ι, Ζερβός Κ, Κοκκινάκης Φ, Τσιφτσής Δ. Διεγχειρητική εντόπιση του ‘λεμφαδένα φρουρού’ σε μελάνωμα του άκρου με τη χορήγηση κυανού του μεθυλενίου ενδοδερμικώς (επιστολή). Ελληνική Χειρουργική 1997;69:485-489.

• Klaus E, Stange R, Kalden M, Krasagakis K, Maurer H. Low molecular thymic peptides improve the deficient immunocytotoxicity of mononuclear cells from tumor patients in vitro. Oncol Rep 1997;4:1343-1347. doi: 10.3892/or.4.6.1343. PMID: 21590251

• Breitbart M, Garbe C, Buttner P, Weiss J, Soyer HP, Stocker U, Krüger S, Breitbart EW, Weckbecker J, Panizzon R, Bahmer F, Tilgen W, Guggenmoos-Holzmann I, Orfanos CE. Ultraviolet light exposure, pigmentary traits and the development of melanocytic naevi and cutaneous melanoma. A case-control study of the German Central Malignant Melanoma Registry. Acta Derm Venereol 1997;77:374-378. doi: 10.2340/0001555577374378. PMID: 9298131

• Eberle J, Krasagakis K, Orfanos CE. Translation initiation factor eIF-4A1 mRNA is consistently overexpressed in human melanoma cells in vitro.
  Int J Cancer 1997;71:396-401. doi: 10.1002/(sici)1097-0215(19970502)71:3<396::aid-ijc16>3.0.co;2-e. PMID: 9139875

• Eckert K, Mayer G, Stange R, Kalden M, Krasagakis K, Maurer H. Effects of thymic peptides, in vitro, on the impaired immunocytotoxicity of peripheral blood mononuclear cells from tumor patients. Int J Oncol 1997;10:481-486. doi: 10.3892/ijo.10.3.481. PMID: 21533400

• Morré DJ, Sun E, Geilen C, Wu LY, de Cabo R, Krasagakis K, Orfanos CE, Morré DM. Capsaicin inhibits plasma membrane NADH oxidase and growth of human and mouse melanoma lines. Eur J Cancer 1996;32A:1995-2003. doi: 10.1016/0959-8049(96)00234-1. PMID: 8943687

• Krasagakis K, Garbe C, Zouboulis CC, Orfanos CE. Growth control of melanoma cells and melanocytes by cytokines. Recent Results Cancer Res 1995;139:169-182. doi: 10.1007/978-3-642-78771-3_12. PMID: 7597288

• Krüger-Krasagakes S, Krasagakis K, Garbe C, Diamantstein T.Production of cytokines by human melanoma cells and melanocytes.Production of cytokines by human melanoma cells and melanocytes. Recent Results Cancer Res. 1995;139:155-168. doi: 10.1007/978-3-642-78771-3_11. PMID: 7597287

• Rieger E, Soyer HP, Garbe C, Buttner P, Kofler R, Weiss J, Stocker U, Krüger S, Roser M, Weckbecker J, et al. Overall and site-specific risk of malignant melanoma associated with nevus counts at different body sites: a multicenter case-control study of the German Central Malignant-Melanoma Registry. Int J Cancer 1995;62:393-397. doi: 10.1002/ijc.2910620406. PMID: 7635564

• Garbe C, Buttner P, Weiss J, Soyer HP, Stocker U, Krüger S, Roser M, Weckbecker J, Panizzon R, Bahmer F, et al.Associated factors in the prevalence of more than 50 common melanocytic nevi, atypical melanocytic nevi, and actinic lentigines: multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society. Associated factors in the prevalence of more than 50 common melanocytic nevi, atypical melanocytic nevi, and actinic lentigines: multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society. J Invest Dermatol 1994;102:700-705. doi: 10.1111/1523-1747.ep12374298. PMID: 8176251

• Garbe C, Buttner P, Weiss J, Soyer HP, Stocker U, Krüger S, Roser M, Weckbecker J, Panizzon R, Bahmer F, et al. Risk factors for developing cutaneous melanoma and criteria for identifying persons at risk: multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society.
  J Invest Dermatol 1994;102:695-699. doi: 10.1111/1523-1747.ep12374280. PMID: 8176250

• Krüger-Krasagakes S, Krasagakis K, Garbe C, Schmitt E, Huls C, Blankenstein T, Diamantstein T. Expression of interleukin 10 in human melanoma.
  Br J Cancer 1994;70:1182-1185. doi: 10.1038/bjc.1994.469. PMID: 7981073

• Krasagakis K, Garbe C, Schrier PI, Orfanos CE. Paracrine and autocrine regulation of human melanocyte and melanoma cell growth by transforming growth factor beta in vitro. Anticancer Res 1994;14:2565-2571. PMID: 7872682

• Krasagakis K, Garbe C, Orfanos CE. Cytokines in human melanoma cells: synthesis, autocrine stimulation and regulatory functions--an overview. Melanoma Res 1993; 3: 425-433. PMID: 8161882

• Krasagakis K, Garbe C, Krüger-Krasagakes S, Orfanos CE. 12-O-tetradecanoylphorbol-13-acetate not only modulates proliferation rates, but also alters antigen expression and LAK-cell susceptibility of normal human melanocytes in vitro. J Invest Dermatol 1993; 100: 653-659. doi: 10.1111/1523-1747.ep12472320. PMID: 8491988

• Eberle J, Krasagakis K, Garbe C, Orfanos CE. Proliferation and morphology of melanoma cells and benign human melanocytes under varying culture conditions. Melanoma Res 1993;3:107-112. PMID: 8518548

• Garbe C, Krasagakis K. Effects of interferons and cytokines on melanoma cells. J Invest Dermatol 1993;100 239S-244S. PMID: 7679433

• Garbe C, Weiss J, Krüger S, Garbe E, Buttner P, Bertz J, Hoffmeister H, Guggenmoos-Holzmann I, Jung EG, Orfanos CE.The German melanoma registry and environmental risk factors implied. The German melanoma registry and environmental risk factors implied. Recent Results Cancer Res 1993;128:69-89. doi: 10.1007/978-3-642-84881-0_6. PMID: 8356335

• Krüger S, Garbe C, Buttner P, Stadler R, Guggenmoos-Holzmann I, Orfanos CE.Epidemiologic evidence for the role of melanocytic nevi as risk markers and direct precursors of cutaneous malignant melanoma. Results of a case control study in melanoma patients and nonmelanoma control subjects.Epidemiologic evidence for the role of melanocytic nevi as risk markers and direct precursors of cutaneous malignant melanoma. Results of a case control study in melanoma patients and nonmelanoma control subjects. J Am Acad Dermatol 1992;26:920-926. doi: 10.1016/0190-9622(92)70133-z. PMID: 1607409

• Garbe C, Zouboulis CC, Krüger S, Waibel M, Kreuser ED, Stadler R, Orfanos CE. [Combination of interferon-alpha with cytostatic drugs: a potentially successful therapeutic approach in metastatic melanoma] Hautarzt 1992;43:4-10. PMID: 1369746

• Krasagakis K, Garbe C, Krüger S, Orfanos CE. Effects of interferons on cultured human melanocytes in vitro: interferon-beta but not-alpha or -gamma inhibit proliferation and all interferons significantly modulate the cell phenotype. J Invest Dermatol 1991;97:364-372. doi: 10.1111/1523-1747.ep12480767. PMID: 1712824

• Zouboulis CC, Garbe C, Krasagakis K, Krüger S, Orfanos CE. A fluorometric rapid microassay to identify anti-proliferative compounds for human melanoma cells in vitro. Melanoma Res 1991;1:91-95. doi: 10.1097/00008390-199106000-00003. PMID: 1726673

• Kyriakis K, Stavropoulos P, Hatziolou E, Dellidis G, Varelzidis A, Tosca A. Coexistence of pemphigus vulgaris, malignant melanoma and low-grade lymphoma.
  Dermatologica 1991;183:49-52. doi: 10.1159/000247632. PMID: 1769416

• Zouboulis CC, Schroder K, Garbe C, Krasagakis K, Krüger S, Orfanos CE.Cytostatic and cytotoxic effects of recombinant tumor necrosis factor-alpha on sensitive human melanoma cells in vitro may result in selection of cells with enhanced markers of malignancy. Cytostatic and cytotoxic effects of recombinant tumor necrosis factor-alpha on sensitive human melanoma cells in vitro may result in selection of cells with enhanced markers of malignancy. J Invest Dermatol 1990;95(6 Suppl):223S-230S. doi: 10.1111/1523-1747.ep12875823. PMID: 2258639

• Garbe C, Krasagakis K, Zouboulis CC, Schroder K, Krüger S, Stadler R, Orfanos CE. Antitumor activities of interferon alpha, beta, and gamma and their combinations on human melanoma cells in vitro: changes of proliferation, melanin synthesis, and immunophenotype. J Invest Dermatol 1990;95(6 Suppl):231S-237S. doi: 10.1111/1523-1747.ep12875837. PMID: 2124247

• Garbe C, Krüger S, Stadler R, Guggenmoos-Holzmann I, Orfanos CE.Markers and relative risk in a German population for developing malignant melanoma.Markers and relative risk in a German population for developing malignant melanoma.
  Int J Dermatol 1989;28:517-523. doi: 10.1111/j.1365-4362.1989.tb04604.x. PMID: 2583889